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uterosto
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Uterosto might refer to |
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A uterotonic, also known as ecbolic, is an agent used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor, and to reduce postpartum hemorrhage. * Some uterotonics act as analogues of oxytocin (OXT). An oxytocinergic or oxytocic chemical pathway is one responding to oxytocin or its analogues, and an oxytocinergic or oxytocic agent is any of these agents, oxytocin or its analogues, with similar physiologic effect, chemical interaction, or (usually) both. The oxytocin receptor (OXTR) is the binding and activation site of oxytocin. * Some agents may act as indirect oxytocinergics:* 5-HT1A Receptor (5-HT1AR): A protein responsible for inducing the secretion of oxytocin * Serotonergic: A drug which acts upon serotonin and 5-HT1AR, resulting in oxytocin release (e.g., MDMA ("Ecstasy") * Ergoline uterotonics include methylergonovine, ergometrine (and Syntometrine), and acetergamine * Polypeptides include carbetocin and cargutocin * Cloquinozine had been described as an oxytocic agent. * Epostane is another example of a drug described as a contraceptive, oxytocic agent. * U-69,593 inhibits the peripheral, though not central secretion of oxytocin and vasopressin in rats.ProstaglandinsDinoprost * Alprostadil * Prostaglandin F2, prostaglandin E1, carboprost * Fenprostalene in cattle. This compound resembles Enprostil in structure and is a long-acting analogue of PGF2α. * MeteneprostAnalogs of oxytocinUrofollitropin is an analog of oxytocin possessing higher activity * Carbetocin * Demoxytocin * (Thiazolidine-4-carboxylic acid)-oxytocinTocolyticConversely, a tocolytic acts to oppose uterine contractility. These agents may be oxytocinergic in mechanism. For example, atosiban works in this way.Natural foodParsley in large amount may have uterotonic effect |