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synapsin
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The answer SYNAPSIN has 0 possible clue(s) in existing crosswords.
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There are 8 letters in SYNAPSIN ( A1I1N1P3S1Y4 )
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Definitions of synapsin in various dictionaries:
SYNAPSIN - The synapsins are a family of proteins that have long been implicated in the regulation of neurotransmitter release at synapses. Specifically, they a...
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Synapsin might refer to |
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The synapsins are a family of proteins that have long been implicated in the regulation of neurotransmitter release at synapses. Specifically, they are thought to be involved in regulating the number of synaptic vesicles available for release via exocytosis at any one time. Synapsins are present in invertebrates and vertebrates and are somewhat homologous across evaluated vertebrates. * Current studies suggest the following hypothesis for the role of synapsin: synapsins bind synaptic vesicles to components of the cytoskeleton which prevents them from migrating to the presynaptic membrane and releasing neurotransmitter. During an action potential, synapsins are phosphorylated by PKA (cAMP dependent protein kinase), releasing the synaptic vesicles and allowing them to move to the membrane and release their neurotransmitter. * Gene knockout studies in mice (where the mouse is unable to produce synapsin) have had some surprising results. Mice lacking all three synapsins are prone to seizures, |