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valine
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Definitions of valine in various dictionaries:
noun - an essential amino acid found in proteins
noun - an amino acid
VALINE - Valine (symbol Val or V) is an -amino acid that is used in the biosynthesis of proteins. It contains an -amino group (which is in the protonated NH3+...
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Valine description |
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Valine (symbol Val or V) is an -amino acid that is used in the biosynthesis of proteins. It contains an -amino group (which is in the protonated NH3+ form under biological conditions), an -carboxylic acid group (which is in the deprotonated COO form under biological conditions), and a side chain isopropyl group, making it a non-polar aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it: it must be obtained from the diet. Human dietary sources are foods that contain protein, such as meats, dairy products, soy products, beans and legumes. It is encoded by all codons starting with GU (GUU, GUC, GUA, and GUG). * Like leucine and isoleucine, valine is a branched-chain amino acid. In sickle-cell disease, a single glutamic acid in -globin is replaced with valine. Because valine is hydrophobic, whereas glutamic acid is hydrophilic, this change makes the hemoglobin prone to abnormal aggregation. |