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microsome
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The answer MICROSOME has 0 possible clue(s) in existing crosswords.
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Definitions of microsome in various dictionaries:
noun - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA
A small particle in the cytoplasm of a cell, typically consisting of fragmented endoplasmic reticulum to which ribosomes are attached.
MICROSOME - In cell biology, microsomes are vesicle-like artifacts re-formed from pieces of the endoplasmic reticulum (ER) when eukaryotic cells are broken-up in...
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| Possible Dictionary Clues |
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| A small particle in the cytoplasm of a cell, typically consisting of fragmented endoplasmic reticulum to which ribosomes are attached. |
| a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA |
| A fragment of endoplasmic reticulum and attached ribosomes obtained by the centrifugation of homogenized cells. |
| Microsome might refer to |
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| In cell biology, microsomes are vesicle-like artifacts re-formed from pieces of the endoplasmic reticulum (ER) when eukaryotic cells are broken-up in the laboratory; microsomes are not present in healthy, living cells.Microsomes can be concentrated and separated from other cellular debris by differential centrifugation. Unbroken cells, nuclei, and mitochondria sediment out at 10,000 g, whereas soluble enzymes and fragmented ER, which contains cytochrome P450 (CYP), remain in solution (g is the Earth's gravitational acceleration). At 100,000 g, achieved by faster centrifuge rotation, ER sediments out of solution as a pellet but the soluble enzymes remain in the supernatant. In this way, cytochrome P450 in microsomes is concentrated and isolated. Microsomes have a reddish-brown color, due to the presence of the heme. Because of the need for a multi-part protein-system, microsomes are necessary to analyze the metabolic activity of CYPs. These CYPs are highly abundant in livers of rats, |