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mercaptopurine
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The answer MERCAPTOPURINE has 0 possible clue(s) in existing crosswords.
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Definitions of mercaptopurine in various dictionaries:
noun - a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
MERCAPTOPURINE - Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is...
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| A purine analogue, C5H4N4S, that acts as an antimetabolite by interfering with purine synthesis, used primarily in the treatment of acute leukemia. |
| a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia |
| Mercaptopurine description |
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Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis. For ALL it is generally used with methotrexate. It is taken by mouth.Common side effects include bone marrow suppression, liver toxicity, vomiting, and loss of appetite. Other serious side effects include an increased risk of future cancer and pancreatitis. Those with a genetic deficiency in thiopurine S-methyltransferase are at higher risk of side effects. Use in pregnancy may harm the baby. Mercaptopurine * is in the thiopurine and antimetabolite family of medications.Mercaptopurine was approved for medical use in the United States in 1953. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 18.42 to 200.16 USD a month. In the United Kingdom this costs the NHS about 121.13 pounds per month. In the United States the wholesale cost is about 99.16 USD per month as of 2016. |