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macroglobulins
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Definitions of macroglobulins in various dictionaries:
MACROGLOBULINS - A macroglobulin is a plasma globulin of high molecular weight.Elevated levels of macroglobulins (macroglobulinemia) may cause manifestations of exces...
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| Plural form of macroglobulin. |
| Any blood plasma globulin of high molecular weight (usually, greater than 400,000) especially immunoglobulin M. |
| Macroglobulins description |
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A macroglobulin is a plasma globulin of high molecular weight.Elevated levels of macroglobulins (macroglobulinemia) may cause manifestations of excess blood viscosity (as is the case for IgM antibodies in Waldenström macroglobulinemia) and/or precipitate within blood vessels when temperature drops (as in cryoglobulinaemia). * Other macroglobulins include alpha-2 macroglobulin, which is elevated in nephrotic syndrome, diabetes, severe burns, and other conditions, while a deficiency is associated with chronic obstructive pulmonary disease. |