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exonuclease

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Definitions of exonuclease in various dictionaries:

noun - a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid

Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.

EXONUCLEASE - Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that br...

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Possible Dictionary Clues
Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.
a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
An enzyme which removes successive nucleotides from the end of a polynucleotide molecule.

Exonuclease description
Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks phosphodiester bonds at either the 3' or the 5' end occurs. Its close relative is the endonuclease, which cleaves phosphodiester bonds in the middle (endo) of a polynucleotide chain. Eukaryotes and prokaryotes have three types of exonucleases involved in the normal turnover of mRNA: 5' to 3' exonuclease (Xrn1), which is a dependent decapping protein; 3' to 5' exonuclease, an independent protein; and poly(A)-specific 3' to 5' exonuclease.In both archaea and eukaryotes, one of the main routes of RNA degradation is performed by the multi-protein exosome complex, which consists largely of 3' to 5' exoribonucleases.

Exonuclease description

Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks phosphodiester bonds at either the 3' or the 5' end occurs. Its close relative is the endonuclease, which cleaves phosphodiester bonds in the middle (endo) of a polynucleotide chain. Eukaryotes and prokaryotes have three types of exonucleases involved in the normal turnover of mRNA: 5' to 3' exonuclease (Xrn1), which is a dependent decapping protein; 3' to 5' exonuclease, an independent protein; and poly(A)-specific 3' to 5' exonuclease.In both archaea and eukaryotes, one of the main routes of RNA degradation is performed by the multi-protein exosome complex, which consists largely of 3' to 5' exoribonucleases.

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