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endomorphs
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The answer ENDOMORPHS has 0 possible clue(s) in existing crosswords.
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Definitions of endomorphs in various dictionaries:
noun - a heavy person with a soft and rounded body
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| Possible Dictionary Clues |
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| Plural form of endomorph. |
| A person with a soft round build of body and a high proportion of fat tissue. |
| Endomorphs might refer to |
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| Endomorphins are natural opioid neurotransmitters central to pain relief. The two known endomorphins, endomorphin-1 and endomorphin-2, are tetrapeptides, consisting of Tyr-Pro-Trp-Phe and Tyr-Pro-Phe-Phe amino acid sequences respectively. These sequences fold into tertiary structures with high specificity and affinity for the μ-opioid receptor, binding it exclusively and strongly. Bound μ-opioid receptors typically induce inhibitory effects on neuronal activity. Endomorphins exist within the central and peripheral nervous systems, where endomorphin-1 is concentrated in the brain and upper brainstem, and endomorphin-2 is concentrated in the spinal cord and lower brainstem. As the major ligand of the μ-opioid receptor, which is the target receptor of morphine and its derivatives, endomorphins possess significant potential as analgesics with reduced side effects and risk of addiction. |