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daunorubicins
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A synthetic antibiotic that interferes with DNA synthesis and is used in the treatment of acute leukaemia and other cancers. |
Daunorubicins might refer to |
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Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma. It is used by injection into a vein. A liposomal formulation known as liposomal daunorubicin also exists.Common side effects include hair loss, vomiting, bone marrow suppression, and inflammation of the inside of the mouth. Other severe side effects include heart disease and tissue death at the site of injection. Use in pregnancy may harm the baby. Daunorubicin is in the anthracycline family of medication. It works in part by blocking the function of topoisomerase II.Daunorubicin was approved for medical use in the United States in 1979. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 5.79 to 37.18 USD for a 20 mg vial. This amount in the United Kingdom costs the NHS about 55.00 pounds. It was originally isolated from bacteria of the Streptomyces type. |