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carcinosarcoma
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The answer CARCINOSARCOMA has 0 possible clue(s) in existing crosswords.
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Definitions of carcinosarcoma in various dictionaries:
noun - a malignant neoplasm composed of carcinoma and sarcoma extensively intermixed
CARCINOSARCOMA - Carcinosarcomas are malignant tumors that consist of a mixture of carcinoma (or epithelial cancer) and sarcoma (or mesenchymal/connective tissue canc...
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Possible Dictionary Clues |
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Any malignant neoplasm that has characteristics of both a carcinoma and a sarcoma |
a malignant neoplasm composed of carcinoma and sarcoma extensively intermixed |
Carcinosarcoma description |
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Carcinosarcomas are malignant tumors that consist of a mixture of carcinoma (or epithelial cancer) and sarcoma (or mesenchymal/connective tissue cancer). Carcinosarcomas are rare tumors, and can arise in diverse organs, such as the skin, salivary glands, lungs, the esophagus, pancreas, colon, uterus and ovaries.Four main hypotheses have been proposed for the cellular origins of carcinosarcoma, based largely on the pathology of the disease. First, the collision tumor hypothesis, which proposes the collision of two independent tumors resulting in a single neoplasm, based on the observation that skin cancers and superficial malignant fibrous histiocytomas are commonly seen in patients with sun-damaged skin; second, the composition hypothesis, which suggests that the mesenchymal component represents a pseudosarcomatous reaction to the epithelial malignancy; third, the combination hypothesis, which suggests that both the epithelial and mesenchymal components of the tumor arise from a common |