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aromatases
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Possible Dictionary Clues |
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Plural form of aromatase. |
An adrenal enzyme that converts androstenedione and estrone to estrogen. Inhibiting its action is one approach to breast cancer prevention and treatment. |
Aromatases might refer to |
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Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when using external testosterone. They may also be used for chemoprevention in high risk women. * Aromatase is the enzyme that synthesizes estrogen. As breast and ovarian cancers require estrogen to grow, AIs are taken to either block the production of estrogen or block the action of estrogen on receptors. |