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aromatase
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The answer AROMATASE has 0 possible clue(s) in existing crosswords.
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Definitions of aromatase in various dictionaries:
AROMATASE - Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP1...
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| Possible Dictionary Clues |
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| An enzyme that selectively increases the aromaticity of androgen hormones |
| An adrenal enzyme that converts androstenedione and estrone to estrogen. Inhibiting its action is one approach to breast cancer prevention and treatment. |
| Aromatase description |
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| Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1, a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The aromatase enzyme can be found in many tissues including gonads (granulosa cells), brain, adipose tissue, placenta, blood vessels, skin, and bone, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. |