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acrosome

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Definitions of acrosome in various dictionaries:

noun - a process at the anterior end of a sperm cell that produces enzymes to facilitate penetration of the egg

A caplike structure at the anterior end of a spermatozoon that produces enzymes aiding in egg penetration.

noun - a thin sac at the head of a sperm

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Possible Dictionary Clues
A caplike structure at the anterior end of a spermatozoon that produces enzymes aiding in egg penetration.
a process at the anterior end of a sperm cell that produces enzymes to facilitate penetration of the egg
A membrane-bound, darkly staining, granular structure surrounding the anterior end of the nucleus in a spermatozoon, containing enzymes that assist in the penetration of the ovum.
Acrosome description
The acrosome is an organelle that develops over the anterior half of the head in the spermatozoa (sperm cells) of many animals including humans. It is a cap-like structure derived from the Golgi apparatus. Acrosome formation is fully completed 5–10 years after testicular maturation. In Eutherian mammals the acrosome contains digestive enzymes (including hyaluronidase and acrosin). These enzymes break down the outer membrane of the ovum, called the zona pellucida, allowing the haploid nucleus in the sperm cell to join with the haploid nucleus in the ovum.
* This shedding of the acrosome, or acrosome reaction, can be stimulated in vitro by substances a sperm cell may encounter naturally such as progesterone or follicular fluid, as well as the more commonly used calcium ionophore A23187. This can be done to serve as a positive control when assessing the acrosome reaction of a sperm sample by flow cytometry or fluorescence microscopy. This is usually done after staining with a fluoresceinated lectin such as FITC-PNA, FITC-PSA, FITC-ConA, or fluoresceinated antibody such as FITC-CD46.* In the case of globozoospermia (sperm with round heads), the Golgi apparatus is not transformed into the acrosome, causing male infertility.
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