Anagrammer Crossword Solver is a powerful crossword puzzle resource site. We maintain millions of regularly updated crossword solutions, clues and answers of almost every popular crossword puzzle and word game out there. We encourage you to bookmark our puzzle solver as well as the other word solvers throughout our site. Explore deeper into our site and you will find many educational tools, flash cards and plenty more resources that will make you a much better player. This page shows you that DISAGREEMENT is a possible answer for Difference of opinion. You can also see that this clue and answer has appeared in these newspapers and magazines: December 24 2018 The Guardian - Quick crossword, November 6 2017 The Times - Concise, January 13 2015 Newsday.com and more.