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sangers
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Definitions of sangers in various dictionaries:
noun - English biochemist who determined the sequence of amino acids in insulin and who invented a technique to determine the genetic sequence of an organism (born in 1918)
noun - United States nurse who campaigned for birth control and planned parenthood
noun - a temporary fortification for two or three men
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Sangers might refer to |
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Sanger sequencing is a method of DNA sequencing first commercialized by Applied Biosystems, based on the selective incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication. Developed by Frederick Sanger and colleagues in 1977, it was the most widely used sequencing method for approximately 40 years. More recently, higher volume Sanger sequencing has been supplanted by "Next-Gen" sequencing methods, especially for large-scale, automated genome analyses. However, the Sanger method remains in wide use, for smaller-scale projects, validation of Next-Gen results and for obtaining especially long contiguous DNA sequence reads (> 500 nucleotides).* |