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rmine
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There are 5 letters in RMINE ( E1I1M3N1R1 )
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Rmine might refer to |
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MINE in the context of chemotherapy is an acronym for one of the chemotherapy regimens used for treatment of relapsed or refractory aggressive non-Hodgkin's lymphoma and Hodgkin's lymphoma. * Today this regimen is often combined with monoclonal antibody rituximab. In this case the regimen is called R-MINE or MINE-R. * The [R]-MINE regimen consists of:* (R)ituximab - anti-CD20 monoclonal antibody that can kill both normal CD20-expressing B cells and malignant ones; * (M)esna to prevent the development of hemorrhagic cystitis which may otherwise result from ifosfamide administration; * (I)fosfamide - an alkylating antineoplastic agent from oxazafosforine group; * (N)ovantrone - a synthetic antracycline analogue (antraquinone) that is able to intercalate DNA and thus prevent cell division (mitosis); * (E)toposide - a topoisomerase inhibitor. * * |