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CROSSWORD
ANSWER

insurmountable

Searching in Crosswords ...

The answer INSURMOUNTABLE has 4 possible clue(s) in existing crosswords.

Searching in Word Games ...

The word INSURMOUNTABLE is VALID in some board games. Check INSURMOUNTABLE in word games in Scrabble, Words With Friends, see scores, anagrams etc.

Searching in Dictionaries ...

Definitions of insurmountable in various dictionaries:

adj - not capable of being surmounted or overcome

adj - impossible to surmount

Impossible to surmount; insuperable: insurmountable difficulties.

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Keep reading for additional results and analysis below.

Possible Dictionary Clues
Impossible to surmount insuperable: insurmountable difficulties.
too great to be overcome.
not capable of being surmounted or overcome
impossible to surmount
(especially of a problem or a difficulty) so great that it cannot be dealt with successfully:
(esp. of a problem or a difficulty) so great that it cannot be dealt with successfully:
Insurmountable might refer to
A Receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. They are sometimes called blockers; examples include alpha blockers, beta blockers, and calcium channel blockers. In pharmacology, antagonists have affinity but no efficacy for their cognate receptors, and binding will disrupt the interaction and inhibit the function of an agonist or inverse agonist at receptors. Antagonists mediate their effects by binding to the active site or to the allosteric site on a receptor, or they may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity. Antagonist activity may be reversible or irreversible depending on the longevity of the antagonist–receptor complex, which, in turn, depends on the nature of antagonist–receptor binding. The majority of drug antagonists achieve their potency by competing with endogenous ligands or substrates at structurally defined binding sites on receptors.
Anagrammer Crossword Solver is a powerful crossword puzzle resource site. We maintain millions of regularly updated crossword solutions, clues and answers of almost every popular crossword puzzle and word game out there. We encourage you to bookmark our puzzle solver as well as the other word solvers throughout our site. Explore deeper into our site and you will find many educational tools, flash cards and plenty more resources that will make you a much better player. This page shows you that New Labour -10: that can't be got over is a possible clue for insurmountable. You can also see that this clue and answer has appeared in these newspapers and magazines: December 5 2018 The Guardian - Cryptic crossword, December 11 2011 The Telegraph - Cryptic, May 18 2010 The Guardian - Cryptic crossword and more. Insurmountable: A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological resp...