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grignardreagent

grignard reagent

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GRIGNARD REAGENT - A Grignard reagent or Grignard compound is a chemical compound with the generic formula R–Mg–X, where X is a halogen and R is an organic group, n...

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Grignard reagent might refer to
A Grignard reagent or Grignard compound is a chemical compound with the generic formula R–Mg–X, where X is a halogen and R is an organic group, normally an alkyl or aryl. Two typical examples are methylmagnesium chloride H3C–Mg–Cl and phenylmagnesium bromide (C6H5)–Mg–Br. They are a subclass of the organomagnesium compounds
* Grignard compounds are popular reagents in organic synthesis for creating new carbon-carbon bonds. For example, when reacted with another halogenated compound R'–X' in the presence of a suitable catalyst, they typically yield R–R' and the magnesium halide MgXX' as a byproduct; and the latter is insoluble in the solvents normally used. In this aspect, they are similar to organolithium reagents.
* Pure Grignard reagents are extremely reactive solids. They are normally handled as solutions in solvents with an ether group, such as diethyl ether or tetrahydrofuran; which are relatively stable as long as water is excluded. In such a medium, a Grignard reagent is invariably present as a complex with the magnesium atom connected to two ether groups by coordination bonds.
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