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calcin
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The answer CALCIN has 0 possible clue(s) in existing crosswords.
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The word CALCIN is NOT valid in any word game. (Sorry, you cannot play CALCIN in Scrabble, Words With Friends etc)
There are 6 letters in CALCIN ( A1C3I1L1N1 )
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Definitions of calcin in various dictionaries:
CALCIN - Calcineurin (CaN) is a calcium and calmodulin dependent serine/threonine protein phosphatase (also known as protein phosphatase 3, and calcium-depend...
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| Calcin might refer to |
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| Calcineurin (CaN) is a calcium and calmodulin dependent serine/threonine protein phosphatase (also known as protein phosphatase 3, and calcium-dependent serine-threonine phosphatase). It activates the T cells of the immune system and can be blocked by drugs. Calcineurin activates nuclear factor of activated T cell cytoplasmic (NFATc), a transcription factor, by dephosphorylating it. The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, in turn, stimulates the growth and differentiation of the T cell response. Calcineurin is the target of a class of drugs called calcineurin inhibitors, which include cyclosporin, voclosporin, pimecrolimus and tacrolimus. |